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Search Results for " tankyrase in 2 "

5

Compounds

Cat No. Product Name Synonyms Targets
T13078 Tankyrase-IN-2 Wnt/beta-catenin
Tankyrase-IN-2 is a selective, potent and orally active inhibitor of tankyrase with IC50s of 10, 7, and 710 nM for TNKS1, TNKS2 as well as PARP1, respectively
T63508 OM-153
OM-153 is a potent inhibitor of tankyrase, acting on tankyrase 1 (IC50: 13 nM) and tankyrase 2 (IC50: 2 nM), and inhibiting WNT/β-linked protein signaling and proliferation in COLO 320DM.
T72922 TNKS1/2-IN-1
TNKS1/2-IN-1 is a potent inhibitor of tankyrase (TNKS1/2), exhibiting pIC50 values between 7.1-8.2. It is utilized in research targeting cancer, fibrosis, and other hyperproliferative diseases.
T69955 JPI-547 HCl
JPI 547, also known as NOV 1402, is an oral inhibitor of PARP 1/2 and Tankyrase 1/2. JPI-547 demonstrated anti-tumor activity in BRCA-deficient xenograft models as a single-agent and in combination with chemotherapy and ...
T70138 AZ0108
AZ0108 is an orally bioavailable, potent PARP1,2,6 inhibitor that potently inhibits centrosome clustering and is suitable for in vivo efficacy and tolerability studies. AZ0108 has been utilized as in vitro tools and in ...
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